Shargel, Leon 1941- creator Yu, Andrew B. C. 1945- Wu-Pong, Susanna. text bibliography nyu New York McGraw-Hill 2012 6th ed. monographic eng

print

811 pages : 24 cm. illustrations ; Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease. Pharmacy Leon Shargel, Andrew B.C. Yu, Susanna Wu-Pong. Includes bibliographical references and index. Biopharmaceutics Pharmacokinetics Biopharmaceutics Models, Chemical Pharmacokinetics RM 301.4 .Sh52 2012 615/.7 QV 38 9780071603935 (hardcover : alk. paper) 007160393X (hardcover : alk. paper) 9781259071409 2011020446 DNLM/DLC 110512 20150127133428.0 16780199